Guidelines Review Committee
Latest WHO guidelines approved by the Guidelines Review Committee
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WHO guideline on HIV service delivery
This WHO guideline recommends integrating services for hypertension, diabetes, and mental health (including depression, anxiety, and substance use) into...
Abortion care guideline, 2nd ed
The objective of this guideline is to present the complete set of all WHO recommendations and best practice statements relating to abortion. While legal,...
WHO guidelines for malaria
The WHO guidelines for malaria bring together the Organization’s most up-to-date recommendations for malaria in one user-friendly and easy-to-navigate...
Digital adaptation kit for self-monitoring of blood pressure during pregnancy: operational requirements...
The Digital adaptation kit (DAK) for self-monitoring blood pressure during pregnancy enables countries to better help pregnant women manage hypertensive...
Recommendations on the delivery of health services for the prevention and care of sexually transmitted...
WHO's global health sector strategies for HIV, viral hepatitis, and sexually transmitted infections (STIs) aim to reduce gonorrhoea and syphilis ...
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure...
Offering additional pre-exposure prophylaxis (PrEP) choices has the potential to increase uptake and effective use of PrEP, and of HIV prevention overall, as...
WHO's global health sector strategies for HIV, viral hepatitis, and sexually transmitted infections (STIs) aim to reduce gonorrhoea and syphilis...
WHO guidelines for clinical management of arboviral diseases: dengue, chikungunya, Zika and yellow fever
World Health Organization (WHO) has just released the Integrated Guidelines on the Clinical Management of Arboviral Diseases — a crucial step...
WHO recommendations on the management of sickle-cell disease during pregnancy, childbirth and the interpregnancy...
Sickle-cell disease (SCD) is a group of autosomal recessive haemoglobin disorders that results from a gene mutation in the β-subunit of haemoglobin....
The purpose of these guidelines is to provide guidance on the choice of treatment so that patients (adults and children) with CE cysts can be offered...
Clinical management and infection prevention and control for mpox: living guideline, May 2025
This document is for public health specialists, health emergency responders, clinicians, health facility managers, health and care workers and IPC...
Guidelines for the treatment of tungiasis
Tungiasis, a neglected tropical disease caused by the sand flea Tunga penetrans, continues to affect millions of people in vulnerable communities across...
WHO handbook for guideline development
This handbook provides detailed instructions for guideline developers on the following topics:
- application of high-quality methodology for guideline development using systematic search strategies, synthesis and quality assessment of the best available evidence to support the recommendations;
- appropriate collection and management of experts’ declared conflict of interest;
- expert group composition including content experts, methodologists, target users, policy makers, with gender and geographical balance;
- instructions for the management of group process to achieve consensus among experts;
- standards for a transparent decision-making process, taking into consideration potential harms and benefits, end-users' values and preferences;
- developing plans for implementing and adapting guidelines; and
- minimum standards for reporting.
For additional, online, chapters click on Read More on the right-hand side.
Handbook update under development 2025.
The BIGG-REC database is a comprehensive and searchable repository of all WHO/PAHO evidence informed recommendations formulated using GRADE.
The database is searchable according to questions of interest, based on the key components of the question (PICO - population, interventions, comparators, and outcomes).
The aim of BIGG Rec is to help local, provincial, regional and jurisdictional decision-makers and health care workers adapt and adopt evidence-based recommendations.
This platform will feed on continued input from guideline developers which we encourage and users and, thus, its functions will continue to improve and it will be updated regularly to maintain relevance.