Controlled temperature chain: Strategic Roadmap for Priority Vaccines 2017-2020
Overview
The “controlled temperature chain" (CTC) is a specific short-term approach to vaccine management that allows vaccines to be kept at temperatures above the long-term +2° to +8° C storage condition for a limited period of time under monitored and controlled conditions appropriate to the stability of the antigen.
The CTC Strategic Roadmap for Priority Vaccines addresses supply and programmatic issues, aiming for CTC priority vaccines to become licensed for CTC use and facilitating uptake of the CTC vaccine delivery approach. This roadmap focuses primarily on four vaccine types selected by the Working Group (CTC-WG) and endorsed by Immunization Practices Advisory Committee (IPAC) in February 2017.
In 2020, the Strategic Roadmap for CTC Priority Vaccines was reviewed by the CTC Working Group. Typhoid Conjugate Vaccine (TCV) was added as an additional priority vaccine and the CTC-WG confirmed that the commitments outlined in the Roadmap are still relevant and valid for an extended time period through 2024, in view of the many targets still not being met.
