Emerging evidence on additional doses of COVID-19 vaccines and their safety

Overview

This global consultation sought to address key questions related to the safety and need for additional doses of COVID-19 vaccines.

Research to date suggests some vaccines have been shown to be associated with myocarditis in young adult males, though the risk/benefit of COVID-19 vaccination remains favourable. Improving pharmacovigilance systems and systemic collection of real-world safety and effectiveness data is critical to continue updating these assessments, especially as younger populations are included in vaccination schedules and boosters are offered to key populations. Research to understand the pathophysiology of these severe adverse events will also provide support for any risk/benefit assessments. Overall, international coordination and sharing of data and analyses remains essential.