Requirements for meningococcal polysaccharide vaccine, Annex 6, TRS No 658
Requirements for Biological Substances No. 23 (Addendum 1980)

Overview
The WHO Expert Committee on Biological standardization, in 1975, adopted the Requirements for Meningococcal polysaccharide vaccine, which were published in its 27th report. At that time it was recognised that the technology involved in the quality control of such vaccines was changing rapidly but the Requirements were written because meningoccal meningitis is a serious problem in many countries and national health authrorities, particularly in developing countries, had requested guidelines for quality control.
In order to avoid references to several publications, the ammendments published on the 28th and 29th reports of the ECBS are included in the present ammendment.
Full version of the WHO Technical Report Series N° 658 (part 2)