Optimal place of treatment for young infants aged less than 2 months presenting with any low mortality risk sign of possible serious bacterial infection
14 April 2021
| Technical document
Overview
Among young infants < 2 months old with only one low-mortality risk PSBI sign (high body temperature ≥38oC, severe chest in drawing, fast breathing of ≥ 60 breaths per minutes in 1-6 days old infants) presenting to outpatient/emergency department of a hospital (Population), does outpatient treatment with injectable gentamicin for 2 days or 7 days (as per WHO/national guidelines) and oral amoxicillin for 7 days (Intervention), compared to the currently recommended inpatient hospital treatment initiated with injectable ampicillin and gentamicin and supportive care (Control), result in lower rates of poor clinical outcome (death within 2 weeks of initiation of treatment, deterioration during the 7-day treatment period, or persistence of the presenting sign of CSI at the end of the 7-day treatment period) (Outcome).
WHO Team
Child Health and Development (CHD),
Maternal, Newborn, Child & Adolescent Health & Ageing (MCA)
Editors
WHO
Number of pages
3