Guidelines for the safe production and quality control of poliomyelitis vaccines, Annex 3, TRS No 1028

Overview

At its sixty-ninth meeting in 2018, the WHO Expert Committee on Biological Standardization recommended the adoption of the WHO Guidelines for the safe production and quality control of poliomyelitis vaccines.

These Guidelines outline the biosafety measures required for poliomyelitis vaccine production and quality control during the final poliovirus containment stage (Phase III) as defined in the third edition of the WHO Global Action Plan to minimize poliovirus facility-associated risk after type-specific eradication of wild polioviruses and sequential cessation of oral polio vaccine use (GAPIII).

Full version of the  WHO Technical Report Series N° 1028