WHO/BS/2022.2431: Collaborative study: Calibration of 1st WHO Reference Reagent for Tetanus Antitoxin Equine for use in Flocculation Test

Overview

We report here the results of a study for the characterization of a preparation of tetanus antitoxin equine (coded 21/230) and its fitness for purpose as a standardized reagent for the flocculation (Lf) test. The candidate reference reagent was characterised using the Ramon flocculation method, standardized using the 3rd International Standard (IS) for Tetanus Toxoid for use in Flocculation Test (16/302).