INN Radical Book 2015
Names for radicals, groups & others Comprehensive list
28 February 2015
| Publication

Overview
As a general rule, since 1975 INNs are selected for the active moiety of pharmaceutical
substances. In the case of INNs of salts and esters it is left to the user to devise their names
from the INN in conformity with normal chemical practice. Separate names for salts and
esters derived from this procedure are not published. The same approach should be
followed in the case of combination products. In all those situations, names are referred to
as International Nonproprietary Name Modified INNM.
Some of the radicals and groups involved are, however, of such complexity that, shorter
nonproprietary names are selected for these inactive moieties, and published in proposed
lists under the title "names for radicals and groups". If a "radical and group name" is used in
conjunction with an INN, it is also referred to as an INNM.
In some cases, a name of an INN Radical describes more than one substituent, e.g. (names in
Latin) acefuras, aceponas, enbutas, stinopras,… Alphabetical list of currently used names for
radicals and groups is given in the main part of the document, while the names of elements and
chemical groups that were published together with INNs are given in Annex 1.
For further details on the INNM, please refer to the INN Working Document 05.167/3
"International Nonproprietary Names Modified" which can be downloaded from the INN
Programme website.
WHO Team
INN and Classification of Medical Products (INN)
Editors
International Nonproprietary Name (INN) Programme
Number of pages
80
Reference numbers
WHO Reference Number: WHO/EMP/RHT/TSN/2015.1
Copyright
© World Health Organization 2015