The WHO maternal, newborn, child and adolescent health (MNCAH) e-handbook is a vital resource for ministry of health programme managers, offering essential guidance for implementing effective health programmes. It provides concise overviews of key activities and interventions along the life course. By referencing relevant WHO documents, the e-handbook ensures that programme managers have access to evidence-based strategies and best practices tailored to various contexts. This streamlined approach supports efficient programme design and execution, ultimately helping to enhance health outcomes and achieve universal health coverage goals. This handbook contains a prioritised list of documents; for a full list of documents go to the: