Ensuring ethical standards and procedures for research with human beings

Research ethics govern the standards of conduct for scientific researchers. It is important to adhere to ethical principles in order to protect the dignity, rights and welfare of research participants. As such, all research involving human beings should be reviewed by an ethics committee to ensure that the appropriate ethical standards are being upheld. Discussion of the ethical principles of beneficence, justice and autonomy are central to ethical review.

WHO works with Member States and partners to promote ethical standards and appropriate systems of review for any course of research involving human subjects. Within WHO, the Research Ethics Review Committee (ERC) ensures that WHO only supports research of the highest ethical standards. The ERC reviews all research projects involving human participants supported either financially or technically by WHO. The ERC is guided in its work by the World Medical Association Declaration of Helsinki (1964), last updated in 2013, as well as the International Ethical Guidelines for Biomedical Research Involving Human Subjects (CIOMS 2016).

Guidelines

WHO guidance on the ethics of health research priority setting
This guidance aims to synthesize current good practice for incorporating ethics into health research priority setting. It is relevant to anyone making...
The ethics of health research priority setting

The resources available for health research at any given time – including money but also time, infrastructure and personnel – are scarce. Not...

Standards and operational guidance for ethics review of health-related research with human participants

This document is intended to provide guidance to research ethics committees on which organizations rely to review and oversee the ethical aspects of research,...

Tool

WHO tool for benchmarking ethics oversight of health-related research involving human participants 
This tool is intended to assist countries in evaluating their capacity to provide appropriate ethical oversight of health-related research.