Key resources

• CREATE bio example: target product profile (TPP)  National Institute of Neurological Disorders and Stroke
• What’s the regulatory value of a target product profile? Trends Biotechnol 2017
• Note for guidance on pharmaceutical development European Medicines Agency, 2009
• Vaccine development process map UK Medical Research Council
• Constructing target product profiles (TPPs) to help vaccines overcome post-approval obstacles Vaccine 2010