Mental Health, Brain Health and Substance Use
Our work involves mental health promotion and the prevention of mental, neurological and substance use disorders. We support the expansion of access to affordable, quality care for everyone who needs it.

Pharmacological interventions in adolescents with bipolar disorder

2023 updated

Psychotropic medicines (antipsychotic medicines, namely aripiprazole, olanzapine, quetiapine, risperidone, and mood stabilizers, namely lithium) should be considered under specialist supervision for adolescents with bipolar disorder (current episode manic), carefully balancing effectiveness, side-effects and individual preference.
Strength of recommendation: CONDITIONAL
Certainty of evidence: LOW

[2012]

Recommendation(s)

Second-generation antipsychotics (with the exception of clozapine which is indicated for treatment resistant psychosis) can be offered for the treatment of psychotic disorders (including schizophrenia). There is no clinically relevant advantage of one second-generation antipsychotic over others and choice should be based on availability, cost, patient preferences and possible adverse effects associated with each medication.
Strength of recommendation: LOW
Quality of evidence: CONDITIONAL