Mental Health, Brain Health and Substance Use
Our work involves mental health promotion and the prevention of mental, neurological and substance use disorders. We support the expansion of access to affordable, quality care for everyone who needs it.
Psychosis and bipolar disorders
Evidence-based recommendations for management of psychosis and bipolar disorders in non-specialized health settings
- Antipsychotic medicines for psychotic disorders
- Combination of two or more antipsychotic medications for psychotic disorders
- Duration of antipsychotic treatment in individuals with a first psychotic episode
- Duration of maintenance treatment with antipsychotics or mood stabilizers in individuals with bipolar disorder
- Role of Depot antipsychotic medicine in individuals requiring long-term antipsychotic treatment for psychotic disorders
- Role of anticholinergic medications in patients requiring long-term antipsychotic treatment for psychotic disorders
- Pharmacological interventions in adolescents with psychotic disorders
- Pharmacological interventions in adolescents with bipolar disorder
- Antipsychotics and mood stabilizers in individuals with bipolar mania
- Antipsychotics and mood stabilizers (lithium, valproate, or carbamazepine) for maintenance treatment of bipolar disorder
- Antidepressant medicines in individuals with a depressive episode in bipolar disorder
- Psychoeducation, family interventions and cognitive-behavioural therapy
- Recovery-oriented psychosocial strategies enhancing independent living and social skills (such as life skills and social skills training)
- Recovery-oriented strategies enhancing vocational and economic inclusion (such as supported employment)
- Psychosocial interventions for carers of persons with psychosis or bipolar disorder
Related health topics
Publications

24 June 2019
mhGAP Intervention Guide - Version 2.0
This is the second version (2016) of the mhGAP Intervention Guide (mhGAP-IG) for mental, neurological and substance use (MNS) disorders in non-specialist...

1 January 2008
mhGAP Mental Health Gap Action Programme
Mental, neurological and substance use disorders are highly prevalent and burdensome globally. The gap between what is urgently needed and what is available...